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INCI Name: |
Vitis Vinefera (Grape) Seed Extract |
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| Part Used: |
Seeds |
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| Chemistry: |
95% Proanthocyanidins - phenolic compounds |
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in the form of polymers or oligomers, built of |
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flavan-3-ol units, such as catechin, epicatechin, |
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gallocatechin, epigallocatechin, afzelechin and |
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epiafzelechin. |
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Plant |
The grapevine is a perennial plant |
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Description: |
grown in warm, temperate regions of the |
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world. It produces clusters of pale |
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green flowers. The fruit has green, yellow or |
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reddish-purple skins and two to four seeds |
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inside the pulpy flesh. |
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Grape Seed |
Studies have indicated the following: |
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Attributes: |
Powerful antioxidant: topical use protects |
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against the effects of aging by preventing |
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free radical damage. (2) |
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Antiwrinkle: decreases enzyme attacks |
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that weaken and destroy collagen. Provides |
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capillary protective action to skin, resulting |
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in enhanced elasticity and resiliency. |
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Protects against sun damage: topical use |
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Inhibits UV-C radiation-induced peroxidation |
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activity (4) |
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Promotes Hair Growth: topical use promotes |
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proliferation of mouse hair epithelial cells. (1,3,5) |
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Applications: |
Skin conditioner |
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Shampoo |
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Conditioner |
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| References:ences: |
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1.Takahashi T, Yokoo Y, Inoue T and Ishii A. "Toxicological Studies on |
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Procyanidin B-2 for External Application as a Hair Growing Agent," |
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Food and Chemical Toxicology 1999;37:545-552 |
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2. Zhoa Jifu, Wang Jiannong, Chen Yngjie and Agarwal Rajesh, "Anti-tumor |
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promoting actibity of a polyphenolic fraction isolated from grape seeds in the |
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mouse skin two-stage initiation-promotion protocol and identification |
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of procyanidin B5-3'-gallate as the most effective antioxidant constituent," |
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Carcinogenesis 1999;20:1737-1745 |
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3. Takahashi Tomoya, Kamiya Toshikazu , Hasegawa Atsuhiro , and |
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Yokoo Yoshiharu, "Procyanidin Oligomers Selectively and Intensively |
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Promote Proliferation of Mouse Hair Epithelial Cells In Vitro |
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and Activate Hair follicle Growth In Vivo," The Society for |
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Investigative Dermatology, Inc. 1998;78:428-32 |
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4. Bouhamidi Rachid, Prevost Birginie, Nouvelot Andre, "High protection |
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by grape seed proanthocyanidins (GSPC) of polyunsaturated fatty acids |
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against UV-C induced peroxidation," Academie des sciences |
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1998;321:31-38 |
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5. Takahashi Tomoya , Kamiya Toshikazu and Yokoo Yoshiharu, |
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"Proanthocyanidins from Grape Seeds Promote Proliferation of |
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Mouse Hair follicle Cells In vitro and Convert Hair Cycle In vivo," |
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Acta Derm Venereol 1998;78:428-32 |
